Cloning and Characterization of a Constitutive Lysophosphatidic Acid Acyltransferase 2 (LPAT2) Gene from Tropaeolum majus L~!2009-07-22~!2009-09-25~!2010-03-12~!
نویسندگان
چکیده
منابع مشابه
Human Lysophosphatidic Acid Acyltransferase
Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate (LPA)) is a phospholipid with diverse biological activities. The mediator serves as an intermediate in membrane phospholipid metabolism but is also produced in acute settings by activated platelets. LPA is converted to phosphatidic acid, itself a lipid mediator, by an LPA acyltransferase (LPAAT). A human expressed sequence tag was identified ...
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Nasturtium (Tropaeolum majus L.) contains high concentrations of benzylglcosinolate. We found that a hydrolysis product of benzyl glucosinolate-the benzyl isothiocyanate (BITC)-modulates the intracellular localization of the transcription factor Forkhead box O 1 (FOXO1). FoxO transcription factors can antagonize insulin effects and trigger a variety of cellular processes involved in tumor suppr...
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Lysophosphatidic acid acyltransferase (LPAAT-β) is a phosphatidic acid (PA) generating enzyme that plays an essential role in triglyceride synthesis. However, LPAAT-β is now being studied as an important regulator of cell growth and differentiation and as a potential therapeutic target in cancer since PA is necessary for the activity of key proteins such as Raf, PKC-ζ and mTOR. In this report w...
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ژورنال
عنوان ژورنال: The Open Plant Science Journal
سال: 2010
ISSN: 1874-2947
DOI: 10.2174/1874294701004010007